This Shrimp Casserole is a delightful and comforting dish that brings together tender shrimp in a creamy sauce, topped with a crispy breadcrumb layer. Perfect for both busy weeknights and festive gatherings, this casserole combines flavors that will please everyone at the table. Its quick preparation and satisfying taste make it an instant favorite for seafood lovers.

Why You’ll Love This Recipe
- Quick to Prepare: With just 35 minutes from start to finish, you can have a delicious meal ready in no time.
- Family-Friendly Flavor: The creamy sauce and cheesy topping make this dish appealing to both kids and adults alike.
- Versatile Dish: This Shrimp Casserole works great for any occasion, whether it’s a casual dinner or a special celebration.
- Easy Cleanup: One casserole dish means less mess in the kitchen, allowing you more time to enjoy your meal.
- Nutritious Option: Packed with protein and essential nutrients, this casserole is a healthier choice for dinner.
Tools and Preparation
To make this Shrimp Casserole efficiently, you’ll need a few essential tools. Knowing how to use them will streamline your cooking process.
Essential Tools and Equipment
- Casserole dish
- Large pot
- Colander
- Mixing bowl
- Baking sheet (for broiling)
Importance of Each Tool
- Casserole dish: Perfectly accommodates all ingredients while ensuring even cooking.
- Large pot: Ideal for boiling shrimp quickly without overcrowding, resulting in perfectly cooked seafood.
- Mixing bowl: Allows you to combine ingredients easily without making a mess.
Ingredients
For the Shrimp Mixture
- 2 pounds large shrimp (21-24 count), peeled and deveined
- 1 tablespoon Old Bay seasoning, plus 1 tablespoon salt for cooking water
- 2/3 cup mayonnaise
- 1/2 teaspoon garlic powder
- 1/2 teaspoon ground black pepper
For the Topping
- 1 tablespoon butter, plus more to grease the pan
- 1/2 cup panko bread crumbs
- 4 ounces shredded mozzarella cheese
- 4 ounces shredded medium cheddar cheese
How to Make Shrimp Casserole
Step 1: Preheat the Oven
Preheat your oven to 375°F (190°C). Grease a 2 1/2 quart casserole dish with butter to prevent sticking.
Step 2: Cook the Shrimp
Bring a large pot of salted water to a boil. Add Old Bay seasoning.
Add shrimp and cook until opaque, about 30 seconds.
Drain the shrimp using a colander and transfer them to a mixing bowl.
Step 3: Combine Ingredients
In the bowl with the shrimp:
Add mayonnaise, garlic powder, and black pepper. Stir to coat the shrimp evenly.
Mix in mozzarella and cheddar cheeses until well combined.
Transfer this mixture into your prepared casserole dish.
Step 4: Prepare the Topping
Melt butter in a small saucepan or microwave.
Stir in panko bread crumbs until they are evenly coated in butter.
Sprinkle the breadcrumb mixture over the shrimp mixture in the casserole dish.
Step 5: Bake and Broil
Bake uncovered for 13-15 minutes or until the center reaches 145°F.
For added crispiness, broil for an additional 1-2 minutes to brown the crumbs.
Let it rest for 15 minutes before serving to allow flavors to meld together.
Enjoy your delicious homemade Shrimp Casserole!
How to Serve Shrimp Casserole
Serving your Shrimp Casserole can elevate the dining experience. With a few thoughtful touches, you can make this dish even more enjoyable for family and guests.
Individual Portions
- Serve in ramekins for a personal touch. This makes it easy for guests to enjoy their own serving.
Garnish with Fresh Herbs
- Sprinkle chopped parsley or chives on top. This adds freshness and color to the dish.
Pair with Lemon Wedges
- Offer lemon wedges on the side. A squeeze of lemon enhances the flavors and adds brightness.
Accompany with Hot Sauce
- Set out a bottle of hot sauce. It allows guests to customize their spice level.
Serve with a Side Salad
- A light green salad complements the richness of the casserole. Consider a simple vinaigrette dressing for balance.
Offer Crusty Bread
- Provide slices of crusty bread for dipping. This is great for soaking up the creamy sauce.

How to Perfect Shrimp Casserole
To ensure your Shrimp Casserole turns out perfectly every time, consider these tips.
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Choose fresh shrimp: Fresh shrimp enhances flavor and texture. Look for shrimp that smell like the ocean, not fishy.
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Don’t overcook shrimp: Cook shrimp just until opaque. Overcooking can make them tough and rubbery.
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Use quality cheese: Opt for fresh mozzarella and aged cheddar. This will create a richer flavor profile in your casserole.
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Adjust seasoning carefully: Taste as you go! Adjust Old Bay seasoning based on your preference for spice.
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Let it rest before serving: Allowing the casserole to sit for 15 minutes lets flavors meld and makes it easier to serve.
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Experiment with toppings: Consider adding crushed crackers or different herbs mixed into panko for added crunch and flavor.
Best Side Dishes for Shrimp Casserole
Pairing your Shrimp Casserole with complementary side dishes can enhance your meal. Here are some great options to consider.
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Garlic Bread: Warm garlic bread is perfect for soaking up any leftover sauce from the casserole.
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Coleslaw: A crunchy coleslaw adds freshness and texture that balances the creamy casserole.
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Steamed Asparagus: Lightly steamed asparagus provides a healthy option with a nice crunch that pairs well with shrimp.
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Rice Pilaf: Fluffy rice pilaf is an excellent base to serve under your casserole, absorbing delicious flavors.
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Roasted Vegetables: A mix of seasonal roasted vegetables adds color and nutrients while complementing the rich flavors of shrimp.
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Quinoa Salad: A quinoa salad packed with veggies offers a nutritious and hearty side that contrasts nicely with the casserole’s creaminess.
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Cornbread: Sweet cornbread is a delightful addition, offering a comforting contrast to savory dishes.
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Mixed Greens Salad: A simple mixed greens salad dressed lightly can refresh your palate after each bite of rich casserole.
Common Mistakes to Avoid
When making Shrimp Casserole, avoiding common pitfalls can enhance your dish. Here are some mistakes to watch out for:
- Overcooking the shrimp: Shrimp cooks quickly. If you leave it in the water for too long, it becomes tough. Aim for just 30 seconds in boiling water.
- Skipping the seasoning: This dish needs flavor! Forgetting to add Old Bay seasoning and salt can result in a bland casserole. Always season your cooking water and shrimp.
- Using the wrong cheese: Not all cheeses melt the same way. Avoid using pre-shredded cheese with additives, which can affect texture. Stick with fresh mozzarella and cheddar.
- Ignoring resting time: Allowing the casserole to rest for 15 minutes after baking helps the flavors meld and makes serving easier. Don’t rush this step!
- Not greasing the pan: A sticky casserole is no fun! Grease your dish thoroughly to prevent sticking and ensure easy serving.

Storage & Reheating Instructions
Refrigerator Storage
- Store in an airtight container for up to 3 days.
- Cool completely before refrigerating.
Freezing Shrimp Casserole
- Freeze in a freezer-safe container for up to 2 months.
- Cover tightly with plastic wrap or foil to prevent freezer burn.
Reheating Shrimp Casserole
- Oven: Preheat to 350°F (175°C) and bake covered with foil until heated through, about 20 minutes.
- Microwave: Heat in short intervals of 1-2 minutes, stirring in between until warm.
- Stovetop: Warm gently over low heat, stirring occasionally until hot.
Frequently Asked Questions
Here are some common questions about Shrimp Casserole:
What type of shrimp should I use for Shrimp Casserole?
For best results, use large shrimp (21-24 count), peeled and deveined. Fresh or frozen both work well.
Can I make Shrimp Casserole ahead of time?
Yes! You can prepare it a day in advance and store it in the refrigerator before baking.
Is this Shrimp Casserole recipe gluten-free?
To make this dish gluten-free, use gluten-free breadcrumbs instead of panko.
How can I customize my Shrimp Casserole?
Feel free to add vegetables like bell peppers or spinach for extra nutrients and flavor!
Final Thoughts
This Shrimp Casserole is not only quick to prepare but also incredibly versatile. You can customize it easily by adding your favorite ingredients or adjusting spices. It’s perfect for busy weeknights or special gatherings. Give it a try, and enjoy the delightful combination of flavors!

Shrimp Casserole
- Total Time: 35 minutes
- Yield: Serves approximately 6 people 1x
Description
Indulge in a comforting Shrimp Casserole that combines tender shrimp with a creamy, cheesy sauce, all topped with crispy breadcrumbs. This easy-to-make dish is perfect for busy weeknights or special occasions, delivering flavors that everyone will love. In just 35 minutes, you can serve up a satisfying meal that not only pleases seafood enthusiasts but also offers a nutritious option packed with protein. With minimal cleanup and versatile serving options, this Shrimp Casserole is sure to become a family favorite.
Ingredients
- 2 pounds large shrimp (peeled and deveined)
- 1 tablespoon Old Bay seasoning
- 2/3 cup mayonnaise
- 1/2 teaspoon garlic powder
- 1/2 teaspoon ground black pepper
- 1 tablespoon butter
- 1/2 cup panko breadcrumbs
- 4 ounces mozzarella cheese (shredded)
- 4 ounces medium cheddar cheese (shredded)
Instructions
- Preheat oven to 375°F (190°C) and grease a casserole dish with butter.
- Boil salted water with Old Bay seasoning, add shrimp, and cook until opaque (about 30 seconds). Drain and transfer to a mixing bowl.
- Mix in mayonnaise, garlic powder, black pepper, and both cheeses until well combined. Transfer to the casserole dish.
- Melt butter and mix with panko breadcrumbs; sprinkle over the shrimp mixture.
- Bake uncovered for 13-15 minutes or until the center reaches 145°F. Broil for added crispiness if desired. Rest for 15 minutes before serving.
- Prep Time: 15 minutes
- Cook Time: 20 minutes
- Category: Main
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: Approximately 1 cup (240g)
- Calories: 420
- Sugar: 1g
- Sodium: 900mg
- Fat: 24g
- Saturated Fat: 10g
- Unsaturated Fat: 14g
- Trans Fat: 0g
- Carbohydrates: 25g
- Fiber: 1g
- Protein: 28g
- Cholesterol: 220mg
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